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Granzyme K Monoclonal antibody, PBS Only

Granzyme K Monoclonal Antibody for IF, IHC, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, mouse

Applications

IF, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

1C3A4

Cat No : 67272-1-PBS

Print datasheet

Synonyms

Fragmentin 3, Granzyme 3, Granzyme K, GZMK, NK Tryp 2, NK tryptase 2, TRYP2

验证数据展示

  • IF Staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IF Staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using Granzyme K antibody (67272-1-Ig, Clone: 1C3A4 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). DAPI (blue). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (GZMK antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (GZMK antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (GZMK antibody) at dilution of 1:1000 (under 4x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

67272-1-Ig

产品信息

67272-1-PBS targets Granzyme K in IF, IHC, ELISA applications and shows reactivity with Human, mouse samples.

Tested Applications IF, IHC, ELISA Application Description
Tested Reactivity Human, mouse
Immunogen Granzyme K fusion protein Ag27297 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name granzyme K (granzyme 3; NK tryptase II)
Synonyms Fragmentin 3, Granzyme 3, Granzyme K, GZMK, NK Tryp 2, NK tryptase 2, TRYP2
Calculated Molecular Weight 29 kDa
GenBank Accession NumberBC035802
Gene Symbol GZMK
Gene ID (NCBI) 3003
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP49863
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune system. There are five human granzymes (granzyme A (GrA), GrB, GrH, GrK and GrM) currently identified, whereas mice have ten known granzymes (GrA-G, GrK, GrM and GrN) (PMID:14499263). Human GrK was first discovered in 1988 after purification from human peripheral blood mononuclear cells. GrK is expressed by cytotoxic T lymphocytes, natural killer T cells (NKT), γδ T cells and CD56bright+ NK cells.