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Granzyme K Monoclonal antibody, PBS Only

Granzyme K Monoclonal Antibody for IHC, IF-P, ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse

Applications

IHC, IF-P, ELISA

Conjugate

Unconjugated

CloneNo.

1C3A4

Cat no : 67272-1-PBS

Print datasheet

Synonyms

GZMK, Granzyme3, Granzyme 3, Fragmentin-3, Fragmentin 3

验证数据展示

  • IF Staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IF Staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using Granzyme K antibody (67272-1-Ig, Clone: 1C3A4 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). DAPI (blue). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (GZMK antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (GZMK antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (GZMK antibody) at dilution of 1:1000 (under 4x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    IHC staining of human tonsillitis using 67272-1-Ig (same clone as 67272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67272-1-Ig (Granzyme K antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67272-1-PBS in a different storage buffer formulation.

产品信息

67272-1-PBS targets Granzyme K in IHC, IF-P, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, IF-P, ELISA Application Description
Tested Reactivity human, mouse
Immunogen Granzyme K fusion protein Ag27297 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name granzyme K (granzyme 3; NK tryptase II)
Synonyms GZMK, Granzyme3, Granzyme 3, Fragmentin-3, Fragmentin 3
Calculated Molecular Weight 29 kDa
GenBank Accession NumberBC035802
Gene Symbol GZMK
Gene ID (NCBI) 3003
RRIDAB_2882541
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP49863
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune system. There are five human granzymes (granzyme A (GrA), GrB, GrH, GrK and GrM) currently identified, whereas mice have ten known granzymes (GrA-G, GrK, GrM and GrN) (PMID:14499263). Human GrK was first discovered in 1988 after purification from human peripheral blood mononuclear cells. GrK is expressed by cytotoxic T lymphocytes, natural killer T cells (NKT), γδ T cells and CD56bright+ NK cells.