验证数据展示
产品信息
67899-1-PBS targets HBB in WB, Indirect ELISA applications and shows reactivity with Human, rabbit samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, rabbit |
免疫原 | HBB fusion protein Ag9216 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | hemoglobin, beta |
别名 | beta globin, CD113t C, HBB, Hemoglobin beta chain, Hemoglobin subunit beta, hemoglobin, beta |
计算分子量 | 147 aa, 16 kDa |
观测分子量 | 14-16 Da |
GenBank蛋白编号 | BC007075 |
基因名称 | HBB |
Gene ID (NCBI) | 3043 |
RRID | AB_2918655 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P68871 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The hemoglobin molecule is a tetramer consisting of two alpha- and two beta-globin-like chains. HBB gene encodes hemoglobin beta chain. The hemoglobin chains, each with its own heme moiety, cooperate in binding and release of oxygen. Hemoglobin monomers have been found in blood and other tissues including macrophages, alveolar epithelial cells and brain. Defects in HBB have been linked to diseases including Sickle cell anemia, Beta-thalassemia, and Heinz body anemias.