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验证数据展示

  • WB analysis of C6 using 82921-1-RR (same clone as 82921-1-PBS)

    WB analysis of C6 using 82921-1-RR (same clone as 82921-1-PBS)

    C6 cells were subjected to SDS PAGE followed by western blot with 82921-1-RR (HCRTR1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82921-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82921-1-RR

    Affinity and Kinetic Characterization of 82921-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82921-1-RR against Human HCRTR1 were performed. The affinity constant is below 1 pM.

HCRTR1 Recombinant antibody, PBS Only

HCRTR1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 82921-1-PBS

产品说明书

CloneNo. 1E18

宿主/亚型

Rabbit / IgG

种属反应性

human, rat

应用

WB, Indirect ELISA

别名

Orexin receptor 1, Ox 1 R, Orexin/Hypocretin receptor type 1, Orexin receptor type 1, Hypocretin receptor type 1

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

82921-1-PBS targets HCRTR1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原 HCRTR1 fusion protein Ag12269 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 hypocretin (orexin) receptor 1
别名 Orexin receptor 1, Ox 1 R, Orexin/Hypocretin receptor type 1, Orexin receptor type 1, Hypocretin receptor type 1
计算分子量 425 aa, 48 kDa
观测分子量54 kDa
GenBank蛋白编号BC074796
基因名称 HCRTR1
Gene ID (NCBI) 3061
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO43613
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The hypocretin receptor 1 (OX1R, also named HCRTR1) is a G protein-coupled receptor and is a critical participant in the regulation of motivated behavior (PMID:28971565). HCRTR1 is associated with the regulation of motivation, reward, and autonomic functions. HCRTR1 shows a selective binding affinity for HCRT1/orexin-A. Moreover, HCRTR1 and HCRTR2 share 64% sequence similarity in humans (PMID:34052813).