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HCRTR1 Recombinant antibody, PBS Only

HCRTR1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1E18

Cat no : 82921-1-PBS

Print datasheet

Synonyms

Orexin receptor 1, Ox 1 R, Orexin/Hypocretin receptor type 1, Orexin receptor type 1, Hypocretin receptor type 1

验证数据展示

  • WB analysis of C6 using 82921-1-RR (same clone as 82921-1-PBS)

    WB analysis of C6 using 82921-1-RR (same clone as 82921-1-PBS)

    C6 cells were subjected to SDS PAGE followed by western blot with 82921-1-RR (HCRTR1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82921-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82921-1-RR

    Affinity and Kinetic Characterization of 82921-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82921-1-RR against Human HCRTR1 were performed. The affinity constant is below 1 pM.

产品信息

82921-1-PBS targets HCRTR1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, rat
Immunogen HCRTR1 fusion protein Ag12269 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name hypocretin (orexin) receptor 1
Synonyms Orexin receptor 1, Ox 1 R, Orexin/Hypocretin receptor type 1, Orexin receptor type 1, Hypocretin receptor type 1
Calculated Molecular Weight 425 aa, 48 kDa
Observed Molecular Weight54 kDa
GenBank Accession NumberBC074796
Gene Symbol HCRTR1
Gene ID (NCBI) 3061
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO43613
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The hypocretin receptor 1 (OX1R, also named HCRTR1) is a G protein-coupled receptor and is a critical participant in the regulation of motivated behavior (PMID:28971565). HCRTR1 is associated with the regulation of motivation, reward, and autonomic functions. HCRTR1 shows a selective binding affinity for HCRT1/orexin-A. Moreover, HCRTR1 and HCRTR2 share 64% sequence similarity in humans (PMID:34052813).