验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue, rat brain tissue |
Planning an IHC experiment? We recommend our IHCeasy HDAC11 Ready-To-Use IHC Kit. HDAC11 primary antibody included.
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
12204-1-AP targets HDAC11 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | HDAC11 fusion protein Ag2848 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | histone deacetylase 11 |
| 别名 | Histone deacetylase 11, HD11, EC:3.5.1.98 |
| 计算分子量 | 347 aa, 39 kDa |
| 观测分子量 | 38 kDa |
| GenBank蛋白编号 | BC009676 |
| 基因名称 | HDAC11 |
| Gene ID (NCBI) | 79885 |
| RRID | AB_3085391 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96DB2 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. At least 4 classes of HDAC were identified. HDAC11 belongs to Class IV HDACs. HDAC11 is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. This antibody is a rabbit polyclonal antibody raised against full length HDAC11 of human origin.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for HDAC11 antibody 12204-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |