HLA-DMA Recombinant antibody, PBS Only

HLA-DMA Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 82899-2-PBS

产品说明书

CloneNo. 230155E7

宿主/亚型

Rabbit / IgG

种属反应性

Human

应用

WB, IHC, Indirect ELISA

hCG_2001572, DMA protein MHC class II antigen Major histocompatibility complex, class II, DM alpha cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha, DMA protein, DMA, D6S222E

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

82899-2-PBS targets HLA-DMA in Indirect ELISA, IHC, WB applications and shows reactivity with Human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 HLA-DMA fusion protein Ag2452 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 major histocompatibility complex, class II, DM alpha
别名 hCG_2001572, DMA protein MHC class II antigen Major histocompatibility complex, class II, DM alpha cDNA FLJ75740, highly similar to Homo sapiens major histocompatibility complex, class II, DM alpha, DMA protein, DMA, D6S222E
计算分子量 261 aa, 29 kDa
观测分子量30 kDa
GenBank蛋白编号BC026279
基因名称 HLA-DMA
Gene ID (NCBI) 3108
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ31604
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). The class II molecules are composed of two non-covalently associated alpha and beta chains. HLA-DMA and HLA-DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.

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