验证数据展示
产品信息
68718-1-PBS targets HMMR in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, IF/ICC, Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | HMMR fusion protein Ag33723 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | hyaluronan-mediated motility receptor (RHAMM) |
| Synonyms | RHAMM, Receptor for hyaluronan-mediated motility, Intracellular hyaluronic acid-binding protein, IHABP, CD168 |
| Calculated Molecular Weight | 84 kDa |
| Observed Molecular Weight | 84 kDa |
| GenBank Accession Number | NM_012484 |
| Gene Symbol | HMMR |
| Gene ID (NCBI) | 3161 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | O75330 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Hyaluronan-mediated motility receptor (HMMR), also termed CD168, was first described by Turley in murine cells . It is reported that HMMR has an extensive coiled-coil structure (CC) that contains multiple sites for interactive partners. Initially, HMMR was considered a novel hyaluronan-mediated motility receptor and a microtubule-associated spindle assembly factor. Full-length human RHAMM is an 85 kDa coiled-coil protein that occurs both in intracellular and extracellular compartments. It has highly restricted and tightly regulated expression in most normal tissues, but is one of a number of oncogenic proteins that are exported to the cell surface in response to tissue stress by unconventional transport mechanisms. (PMID: 36750558, PMID: 30249497)