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HOXA7 Monoclonal antibody

HOXA7 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 67112-1-Ig

产品说明书

CloneNo. 2A7H6

宿主/亚型

Mouse / IgG1

种属反应性

human and More (1)

应用

WB, IF/ICC, ELISA and More (2)

HOX1.1, HOX1, Homeobox protein Hox-A7, Homeobox protein Hox-1A, ANTP

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
CoraLite® Plus 488
规格: 

-/ -


经过测试的应用

Positive WB detected inA431 cells, HCT 116 cells, HepG2 cells, HL-60 cells, HT-29 cells, K-562 cells, SMMC-7721 cells, THP-1 cells, ACHN cells, SiHa cells, NCI-H1299 cells, HEK-293 cells, RKO cells
Positive IF/ICC detected inHepG2 cells
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:10000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

67112-1-Ig targets HOXA7 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
文献引用应用WB, IHC, IF
经测试反应性 human
文献引用反应性human, mouse
免疫原 HOXA7 fusion protein Ag19025 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 homeobox A7
别名 HOX1.1, HOX1, Homeobox protein Hox-A7, Homeobox protein Hox-1A, ANTP
计算分子量 230 aa, 25 kDa
观测分子量 20 kDa
GenBank蛋白编号BC148692
基因名称 HOXA7
Gene ID (NCBI) 3204
RRIDAB_2882416
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP31268
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxa-1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor, which has been shown to play important roles in cell differentiation and embryogenesis. Hoxa-1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, Hoxa-2 is expressed in the mesenchyme and epithelial cells of palate, however its expression is restricted to the tips of the growing palatal shelves. Hoxa-2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, Hoxa-2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. Hoxa-7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. Hoxa-7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.

实验方案

Product Specific Protocols
WB protocol for HOXA7 antibody 67112-1-IgDownload protocol
IF protocol for HOXA7 antibody 67112-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Reprod Sci

CircPAPPA Regulates the Proliferation, Migration, Invasion, Apoptosis, and Cell Cycle of Trophoblast Cells Through the miR-3127-5p/HOXA7 Axis.

Authors - Jun Li
humanWB

J Orthop Surg Res

MiR-920 promotes osteogenic differentiation of human bone mesenchymal stem cells by targeting HOXA7.

Authors - Jun-Pu Zha
human,mouseWB,IHC,IF

Cancer Sci

Homeobox A7 promotes esophageal squamous cell carcinoma progression through C-C motif chemokine ligand 2-mediated tumor-associated macrophage recruitment

Authors - Anqi Feng
  • KD Validated
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