验证数据展示
产品信息
67572-1-PBS targets HSD3B2 in WB, IF/ICC, ELISA applications and shows reactivity with human, pig samples.
经测试应用 | WB, IF/ICC, ELISA Application Description |
经测试反应性 | human, pig |
免疫原 | HSD3B2 fusion protein Ag4291 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
别名 | 3-beta-HSD II, 3-beta-HSD adrenal and gonadal type, 3b HSD, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 |
计算分子量 | 42 kDa |
观测分子量 | 42 kDa |
GenBank蛋白编号 | BC038419 |
基因名称 | HSD3B2 |
Gene ID (NCBI) | 3284 |
RRID | AB_2882785 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P26439 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HSD3B2(3-beta-hydroxy-Delta(5)-steroid dehydrogenase) belongs to the 3-beta-HSD family and catalyzes the oxidation and isomerization of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, thus leading to the formation of all classes of steroid hormones.HSD3B2 is expressed almost exclusively in adrenals and gonads, whereas HSD3B1 is expressed predominantly in placenta and skin(PMID:1682237). Defects in HSD3B2 are the cause of adrenal hyperplasia type 2 (AH2).