验证数据展示
产品信息
82690-2-PBS targets HuR/ELAVL1 in WB, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | HuR/ELAVL1 fusion protein Ag2249 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) |
别名 | ELAVL1, Hu antigen R, ELAV-like protein 1, ELAVL 1, ELAV1 |
计算分子量 | 326 aa, 36 kDa |
观测分子量 | 30-37 kDa |
GenBank蛋白编号 | BC003376 |
基因名称 | HuR/ELAVL1 |
Gene ID (NCBI) | 1994 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q15717 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ELAVL1, also named as HUR, belongs to the RRM elav family. It is involved in 3'-UTR ARE-mediated MYC stabilization. ELAVL1 binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, ELAVL1 binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.