Recombinant Human CD14 protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 |
Not tested |
来源 | HEK293-derived Human CD14 protein Thr20-Met344 (Accession# P08571) with a His tag at the C-terminus. |
基因ID | 929 |
蛋白编号 | P08571 |
预测分子量 | 39.1 kDa |
SDS-PAGE | 45-60 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein preferentially expressed on monocytes and macrophages, and at lower levels on granulocytes. CD14 can also exist as a soluble protein. CD14 acts as a co-receptor for bacterial liposaccharides (LPS). It plays a major role in the inflammatory response of monocytes to LPS.
参考文献:
1. A Haziot, et al. (1988) J Immunol. 141(2):547-52. 2. D L Simmons, et al. (1989) Blood. 73(1):284-9. 3. S D Wright, et al. (1990) Science. 249(4975):1431-3. 4. A Haziot, et al. (1993) J Immunol. 150(12):5556-65.