Recombinant Human CD24 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human CD24 protein Ser27-Gly59 (Accession# P25063-1) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 100133941 |
蛋白编号 | P25063-1 |
预测分子量 | 29.4 kDa |
SDS-PAGE | 38-50 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD24 (known as heat stable antigen) is a small highly glycosylated GPI-linked sialoprotein. It is normally expressed at the surface of most B lymphocytes and differentiating neuroblasts, and it is also up-regulated in a wide variety of cancers. Studies have shown that CD24 functions in the regulation of B-cell apoptosis, leukocyte signal transduction, and leukocyte adhesion.
参考文献:
1. T Suzuki, et al. (2001). J Immunol. May 1;166(9). 2. Yang Liu, Pan Zheng. (2023). Front Immunol. May 9:14:1174789. 3. Yang-Hong Ni, et al. (2020). Curr Gene Ther. 20(2):109-126. 4. Peter Altevogt, et al. (2021). Int J Cancer. Feb 1;148(3):546-559.