Recombinant Human CD30 Ligand/TNFSF8 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2118

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Synonyms

CD30 L, TNFSF 8, TNFSF8, CD30L, CD30-L



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human CD30 Ligand protein Gln63-Asp234 (Accession# P32971) with a rabbit IgG Fc tag at the N-terminus.
基因ID 944
蛋白编号 P32971
预测分子量 46.8 kDa
SDS-PAGE 48-68 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

TNFSF8, also named as CD30LG and CD153, is a member of the tumor necrosis factor (TNF) receptor superfamily. It is the cytokine that binds to TNFRSF8/CD30. It induces proliferation of T-cells. CD30L enhanced the proliferation of CD3-activated T cells, but induced differential responses, including cell death, in several CD30-positive lymphoma-derived cell lines.

参考文献:

1.Ezogelin Oflazoglu, et al. (2009) Adv Exp Med Biol. 647:174-85. 2.Nancy D Marín, et al. (2017) Tuberculosis (Edinb). 102:8-15. 3.Jin Duan, et al. (2019) Int Immunopharmacol. 71:350-360.