Recombinant Human CD5 protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human CD5 protein Arg25-Pro372 (Accession# P06127) with a His tag at the C-terminus. |
基因ID | 921 |
蛋白编号 | P06127 |
预测分子量 | 39.4 kDa |
SDS-PAGE | 42-55 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family. CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells. CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development.
参考文献:
1. J A Ledbetter, et al. (1980) J Exp Med. 152(2):280-95. 2. G S Wood, et al. (1992) Am J Pathol. 141(4):789-95. 3. A Tarakhovsky, et al. (1995) Science. 269(5223):535-7. 4. H S Azzam, et al. (1998) J Exp Med. 188(12):2301-11. 5. P Youinou, et al. (1999) Immunol Today. 20(7):312-6. 6. Chander Raman, et al. (2002) Immunol Res. 26(1-3):255-63.