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Recombinant Human DPP4/CD26 protein (Myc Tag, His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

Myc Tag, His Tag

生物活性

未测试

Cat no : Eg0157

Print datasheet

Synonyms

CD26, ADABP, ADCP 2, ADCP2, ADCP-2

验证数据展示

  • Purity of Recombinant Human DPP4 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human DPP4 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human DPP4 protein Asp34-Pro766 (Accession# P27487) with a Myc tag and a His tag at the C-terminus.
基因ID 1803
蛋白编号 P27487
预测分子量 89.9 kDa
SDS-PAGE 90-120 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD26, also known as DPP4 (dipeptidyl peptidase-4), is a 110 kDa type II cell-surface glycoprotein widely expressed on T cells, activated B cells, activated NK cells and myeloid cells as well as on epithelial cells, fibroblasts, mesothelium, and endothelial cells of a variety of tissues. It has ecto-enzyme activity in its extracellular domain and cleaves amino-terminal dipeptides with either L-proline or L-alanine at the penultimate position. CD26 plays roles in diverse biological processes such as immunoregulation, glucose homeostasis, and tumorigenesis.

参考文献:

1. C Morimoto, et al. (1998) Immunol Rev. 161:55-70.
2. C Klemann, et al. (2016) Clin Exp Immunol. 185(1):1-21.
3. Kelsey Pan, et al. (2021) Cureus. 13(2):e13495.