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Recombinant Human MMP-8 protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0378

Print datasheet

Synonyms

MMP8, CLG1, EC:3.4.24.34, HNC, Matrix metalloproteinase 8

验证数据展示

  • Purity of Recombinant Human MMP-8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human MMP-8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human MMP-8 protein Phe21-Gly467 (Accession# P22894) with a His tag at the C-terminus.
基因ID 4317
蛋白编号 P22894
预测分子量 55.2 kDa
SDS-PAGE 60-90 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

MMP-8(Matrix metalloproteinase-8) an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. The high-serum MMP-8 levels (>100 ng/mL) had poor cancer-specific survival. MMP8 also has prognosis in patients with gastric cancer.

参考文献:

1. Wang H. et al. (2004) Hum Mol Genet. 13(21):2659-69.
2. Sirniö P. et al. (2018) Br J Cancer. 119(2):213-219. 
3. Laitinen A. et al. (2018) Tumour Biol. 40(9):1010428318799266. 
4. Decock J. et al. (2008) BMC Cancer. 8:77. 
5. Lauhio A. et al. (2011) Pharmacol Res. 64(6):590-4.