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Recombinant Human SHBG protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0369

Print datasheet

Synonyms

SHBG, SBP, Sex hormone-binding globulin, Sex steroid binding protein, Sex steroid-binding protein

验证数据展示

  • Purity of Recombinant Human SHBG was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human SHBG was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human SHBG protein Leu30-His402 (Accession# P04278-1) with a His tag at the C-terminus.
基因ID 6462
蛋白编号 P04278-1
预测分子量 44.3 kDa
SDS-PAGE 43-55 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

SHBG (sex hormone-binding globulin), also known as androgen-binding protein (ABP), is the specific transport protein for sex steroid hormones in humans. SHBG is synthesized mainly by the liver and circulates in the blood. Alteration of SHBG levels have been linked to risks of insulin resistance, cardiovascular disease, male infertility and other diseases.

参考文献:

1. Elif Aribas. et al. J Clin Endocrinol Metab. 2021;106(10):2890-2900.
2. Luca Boeri. Et al. Endocr Connect. 2020 Jul;9(7):658-666.