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Recombinant Human SEMA7A protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2005

Print datasheet

Synonyms

CD108, CDw108, John-Milton-Hargen human blood group Ag, Sema K1, Sema L

验证数据展示

  • Purity of Recombinant Human SEMA7A was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human SEMA7A was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human SEMA7A protein Gln45-Ala648 (Accession# O75326-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 8482
蛋白编号 O75326-1
预测分子量 94.7 kDa
SDS-PAGE 85-110 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

SEMA7A, also named CD108 and SEMAL, belongs to the semaphorin family. SEMA7A is the only membrane‐associated glycosylphosphatidylinositol (GPI)‐linked semaphorin and plays a role in the regulation of neuronal axon outgrowth. In addition to its role in guiding axon pathfinding during neuronal development, Sema7A has diverse functions in morphogenesis and immune cell control and regulates T cell responses via the α1β1 integrin receptor.

参考文献:

1. Jing Deng, et al. (2020) CNS Neurosci Ther. Jan;26(1):101-116.
2. R Jeroen Pasterkamp, et al. (2003) Nature. Jul 24;424(6947):398-405.
3. Kazuhiro Suzuki, et al. (2007) Nature. Apr 5;446(7136):680-4.