Recombinant Human CD268/BAFFR protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1922

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Synonyms

TNFRSF13C, BAFF R, BAFF receptor, BAFFR, BAFF-R



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human CD268 protein Ser7-Ala71 (Accession# Q96RJ3-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 115650
蛋白编号 Q96RJ3-1
预测分子量 32.8 kDa
SDS-PAGE 37-52 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

TNFRSF13C (Tumor necrosis factor receptor superfamily member 13C), also known as BAFF-R, BR3, is a widely expressed receptor of important functional relevance for T and B cell responses, represents an attractive target for intervention in autoimmune diseases. The absolute absence of BAFF-R on earlier precursors suggests that a complete BCR positively regulates BAFF-R expression. BAFF/BAFF-R signaling axis in the pathogenesis of autoimmune human diseases and B lineage malignancies have largely prompted studies focusing on BAFF expression.

参考文献:

1. Ye Q, et al. (2004). Eur J Immunol. Oct;34(10):2750-2759. 2. Ng LG, et al. (2004). J Immunol. Jul 15;173(2):807-817. 3. Mihalcik S.A., et al. (2010). J Immunol. Jul 15;185(2):1045-54.