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ICAM3/CD50 Recombinant antibody, PBS Only

ICAM3/CD50 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241417F3

Cat no : 84335-5-PBS

Print datasheet

Synonyms

CDW50, ICAM3, ICAM R, ICAM 3, CD50

验证数据展示

  • WB analysis using 84335-5-RR (same clone as 84335-5-PBS)

    WB analysis using 84335-5-RR (same clone as 84335-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84335-5-RR (ICAM3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84335-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84335-5-RR

    Affinity and Kinetic Characterization of 84335-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84335-5-RR against Human ICAM3/CD50 were performed. The affinity constant is 24.7 nM.

产品信息

84335-5-PBS targets ICAM3/CD50 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name intercellular adhesion molecule 3
Synonyms CDW50, ICAM3, ICAM R, ICAM 3, CD50
Calculated Molecular Weight 547 aa, 60 kDa
Observed Molecular Weight 110-130 kDa
GenBank Accession NumberBC058903
Gene Symbol ICAM3/CD50
Gene ID (NCBI) 3385
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP32942
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Intercellular Adhesion Molecule 3 (ICAM-3), also known as CD50, is a member of the immunoglobulin superfamily. It is a transmembrane glycoprotein that contains an N-terminus extracellular domain, a single transmembrane domain, and a C-terminus cytoplasmic domain. ICAM-3 possesses 2-9 Ig-like C2-type domains in its extracellular region and is known to bind to the leukocyte adhesion protein LFA-1 . This molecule is expressed on leukocytes and epidermal Langerhans cells and plays a significant role in immune cell interactions and T lymphocyte activation.