IFNAR1 Recombinant antibody
IFNAR1 Recombinant Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
230549C8
验证数据展示
经过测试的应用
Positive WB detected in | K-562 cells, HeLa cells, HepG2 cells, HEK-293 cells, A431 cells, Jurkat cells |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
The immunogen of 83002-4-RR is IFNAR1 Fusion Protein expressed in E. coli.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | Fusion Protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | interferon (alpha, beta and omega) receptor 1 |
Synonyms | AVP, CRF2 1, IFN alpha REC, IFN alpha/beta receptor 1, IFN R 1, IFNAR, IFNAR1, IFNBR, IFRC, Type I interferon receptor 1 |
Calculated Molecular Weight | 557 aa, 64 kDa |
Observed Molecular Weight | 80-140 kDa |
GenBank Accession Number | BC021825 |
Gene Symbol | IFNAR1 |
Gene ID (NCBI) | 3454 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | P17181 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.
实验方案
Product Specific Protocols | |
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WB protocol for IFNAR1 antibody 83002-4-RR | Download protocol |
FC protocol for IFNAR1 antibody 83002-4-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |