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验证数据展示

  • FC experiment of U-937 using 98067-1-RR (same clone as 98067-1-PBS)

    FC experiment of U-937 using 98067-1-RR (same clone as 98067-1-PBS)

    1x10^6 U-937 cells were surface stained with 0.25 ug Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR, Clone:230549B1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed. This data was developed using the same antibody clone with 98067-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98067-1-RR

    Affinity and Kinetic Characterization of 98067-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98067-1-RR against Human IFNAR1 were performed. The affinity constant is 1.15 nM.

Anti-Human IFNAR1 Rabbit Recombinant Antibody, PBS Only

IFNAR1 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98067-1-PBS

产品说明书

CloneNo. 230549B1

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98067-1-PBS targets IFNAR1 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interferon (alpha, beta and omega) receptor 1
别名 IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP
计算分子量 557 aa, 64 kDa
GenBank蛋白编号BC021825
基因名称 IFNAR1
Gene ID (NCBI) 3454
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP17181
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.