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验证数据展示

  • WB analysis using 31951-1-AP

    WB analysis using 31951-1-AP

    EL-4 cells were subjected to SDS PAGE followed by western blot with 31951-1-AP (IFN-gamma R1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • IP experiment of EL-4 using 31951-1-AP

    IP experiment of EL-4 using 31951-1-AP

    IP result of anti-IFNGR1 (IP:31951-1-AP, 4ug; Detection:31951-1-AP 1:600) with EL-4 cells lysate 2080 ug.

IFNGR1 Polyclonal antibody

IFNGR1 Polyclonal Antibody for WB, IP, ELISA
Cat No. 31951-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

WB, IP, ELISA

别名

Ifngr, IFN-gamma-R-alpha, IFN-gamma-R1, IFN-gamma receptor 1, IFN-gamma R1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inEL-4 cells
Positive IP detected inEL-4 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31951-1-AP targets IFNGR1 in WB, IP, ELISA applications and shows reactivity with mouse samples.

经测试应用 WB, IP, ELISA Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interferon gamma receptor 1
别名 Ifngr, IFN-gamma-R-alpha, IFN-gamma-R1, IFN-gamma receptor 1, IFN-gamma R1
计算分子量52kDa
观测分子量90 kDa
GenBank蛋白编号NM_010511.3
基因名称 Ifngr1
Gene ID (NCBI) 15979
RRIDAB_3670157
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDP15261
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Interferon-gamam (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)

实验方案

Product Specific Protocols
WB protocol for IFNGR1 antibody 31951-1-APDownload protocol
IP protocol for IFNGR1 antibody 31951-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols