IGFALS Polyclonal antibody, PBS Only

IGFALS Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 24545-1-PBS

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Synonyms



产品信息

24545-1-PBS targets IGFALS in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen IGFALS fusion protein Ag21696 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name insulin-like growth factor binding protein, acid labile subunit
Synonyms
Calculated Molecular Weight 605 aa, 66 kDa
Observed Molecular Weight85 kDa
GenBank Accession NumberBC025681
Gene Symbol IGFALS
Gene ID (NCBI) 3483
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP35858
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

THE ACID-LABILE SUBUNIT (ALS), a liver-derived, GH-dependent, 85-kD glycoprotein, is a key component of the 150-kD IGF circulating ternary complex(PMID: 17726072). The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.