IHCeasy DUSP6 Ready-To-Use IHC Kit
DUSP6 Ready-to-use reagent kit for IHC.
Reactivity
Human
Sample Type
FFPE tissue
Cat No : KHC2521
Synonyms
DUSP6,dual specificity phosphatase 6,EC:3.1.3.16,M
Validation Data Gallery
Product Information
KHC2521 is a ready-to-use IHC kit for staining of DUSP6. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
Product name | IHCeasy DUSP6 Ready-To-Use IHC Kit |
Sample type | FFPE tissue |
Assay type | Immunohistochemistry |
Primary antibody type | Rabbit Recombinant |
Secondary antibody type | Polymer-HRP-Goat anti-Rabbit |
Reactivity | Human |
Kit components
Component | Size | Concentration |
---|---|---|
Antigen Retrieval Buffer | 100 mL | 50× |
Washing Buffer | 100 mL ×2 | 20× |
Blocking Buffer | 5 mL | RTU |
Primary Antibody | 5 mL | RTU |
Secondary Antibody | 5 mL | RTU |
Chromogen Component A | 0.2 mL | RTU |
Chromogen Component B | 4 mL | RTU |
Signal Enhancer | 5 mL | RTU |
Counter Staining Reagent | 5 mL | RTU |
Mounting Media | 5 mL | RTU |
Datasheet | 1 Copy | |
Manual | 1 Copy |
Background Information
Dual specificity phosphatase 6 (DUSP6) is a member of the family of mitogen-activated protein kinase (MAPK) phosphatases, which dephosphorylate and inactivate MAPK. The MAPK pathway is an important signal transduction system that serves cellular processes, such as proliferation, differentiation, migration, and apoptosis. DUSP6 resides at chromosome location 12q22-23, which is one of the candidate loci for susceptibility to bipolar disorder and which encodes a phosphatase selective for extracellular signal-regulated kinase (ERK). DUSP6 inactivates extracellular signal-regulated kinase (ERK), and can act in tumor suppressive pathways, whose expression is reduced in several different types of cancer.
Properties
Storage Instructions | All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. |
Synonyms | DUSP6,dual specificity phosphatase 6,EC:3.1.3.16,M |