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IKBKG Monoclonal antibody, PBS Only

IKBKG Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

1F2E2

Cat No : 66460-1-PBS

Print datasheet

Synonyms

AMCBX1, FIP 3, FIP3, Fip3p, I kappa B kinase subunit gamma, IkB kinase subunit gamma, IKBKG, IKK gamma, IKKAP1, IKKG, IP, IP1, IP2, IPD2, NEMO, NF kappa B essential modifier, NF kappa B essential modulator

验证数据展示

  • WB analysis using 66460-1-Ig (same clone as 66460-1-PBS)

    WB analysis using 66460-1-Ig (same clone as 66460-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66460-1-Ig (IKBKG antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66460-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66460-1-Ig (same clone as 66460-1-PBS)

    IHC staining of human breast cancer using 66460-1-Ig (same clone as 66460-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66460-1-Ig (IKBKG antibody) at dilution of 1:300 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66460-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with IKBKG antibody included
  • IHC staining of human breast cancer using 66460-1-Ig (same clone as 66460-1-PBS)

    IHC staining of human breast cancer using 66460-1-Ig (same clone as 66460-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66460-1-Ig (IKBKG antibody) at dilution of 1:300 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66460-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with IKBKG antibody included
Planning an IHC experiment? We recommend our IHCeasy IKBKG Ready-To-Use IHC Kit. IKBKG primary antibody included.

产品信息

66460-1-PBS targets IKBKG in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity human
Immunogen IKBKG fusion protein Ag13358 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Synonyms AMCBX1, FIP 3, FIP3, Fip3p, I kappa B kinase subunit gamma, IkB kinase subunit gamma, IKBKG, IKK gamma, IKKAP1, IKKG, IP, IP1, IP2, IPD2, NEMO, NF kappa B essential modifier, NF kappa B essential modulator
Calculated Molecular Weight 48 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberBC012114
Gene Symbol IKBKG
Gene ID (NCBI) 8517
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y6K9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

IKBKG, also named as FIP3, NEMO, IKKAP1 and IKKG, is specifically phosphorylate serine or threonine residues that are followed by a proline residue. IKBKG is regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways.