Anti-Mouse IL-13 Rabbit Recombinant Antibody
IL-13 Uni-rAbTM Recombinant Antibody for FC (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
Mouse
Applications
FC (Intra)
Conjugate
Unconjugated
CloneNo.
2C14
验证数据展示
经过测试的应用
| Positive FC (Intra) detected in | PMA and ionomycin stimulated C57BL/6 Th2-polarized splenocytes |
| Positive FC detected in | PMA and ionomycin stimulated C57BL/6 Th2-polarized splenocytes |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
98003-1-RR targets IL-13 in FC (Intra) applications and shows reactivity with Mouse samples.
| Tested Applications | FC (Intra) Application Description |
| Tested Reactivity | Mouse |
| Immunogen | Recombinant protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | interleukin 13 |
| Synonyms | Il13, IL-13, interleukin 13, Interleukin-13, 2C14, Il 13 |
| Calculated Molecular Weight | 14 kDa |
| GenBank Accession Number | NM_008355 |
| Gene Symbol | IL-13 |
| Gene ID (NCBI) | 16163 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P20109 |
| Storage Buffer | PBS with 0.09% sodium azide. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Interleukin 13 (IL-13) is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. IL-13 up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. IL-13 inhibits the production of a series of cytokines like IL-1, IL-6, TNF-alpha, and IL-8 by activated human monocytes. IL-13 induces IFN-gamma production by NK cells. IL-13 is thought to be important cytokine in the pathogenesis of asthma, and more recently has been shown to play a pivotal role in a number of fibrotic diseases including hepatic and pulmonary fibrosis, and nodular sclerosing Hodgkin's disease.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for IL-13 antibody 98003-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
