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验证数据展示

  • IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 18104-1-AP (IL20 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 18104-1-AP (IL20 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 18104-1-AP (same clone as 18104-1-PBS)

    WB analysis of HEK-293 using 18104-1-AP (same clone as 18104-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 18104-1-AP (IL20 Antibody) at dilution of 1:700 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

IL-20 Polyclonal antibody, PBS Only

IL-20 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 18104-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

18104-1-PBS targets IL-20 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 IL-20 fusion protein Ag12447 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin 20
别名
计算分子量 406 aa, 44 kDa
GenBank蛋白编号BC074949
基因名称 IL-20
Gene ID (NCBI) 50604
RRIDAB_2878501
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NYY1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 receptor (IL-20R) and IL-20 are expressed in several normal tissue types, including the lung, skin, and kidney. IL-20 is a cytokine structurally related to interleukin 10. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 can stimulate STAT3 activation in keratinocytes. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells. IL-20 is highly associated with potent inflammatory diseases such as psoriasis, contact hypersensitivity, rheumatoid arthritis, and atherosclerosis.