• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

IL-20 Polyclonal antibody, PBS Only

IL-20 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 18104-1-PBS

Print datasheet

Synonyms

验证数据展示

  • IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 18104-1-AP (IL20 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    IHC staining of human tonsillitis using 18104-1-AP (same clone as 18104-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 18104-1-AP (IL20 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 18104-1-AP (same clone as 18104-1-PBS)

    WB analysis of HEK-293 using 18104-1-AP (same clone as 18104-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 18104-1-AP (IL20 Antibody) at dilution of 1:700 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18104-1-PBS in a different storage buffer formulation.

产品信息

18104-1-PBS targets IL-20 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen IL-20 fusion protein Ag12447 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name interleukin 20
Synonyms
Calculated Molecular Weight 406 aa, 44 kDa
GenBank Accession NumberBC074949
Gene Symbol IL-20
Gene ID (NCBI) 50604
RRIDAB_2878501
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NYY1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 receptor (IL-20R) and IL-20 are expressed in several normal tissue types, including the lung, skin, and kidney. IL-20 is a cytokine structurally related to interleukin 10. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 can stimulate STAT3 activation in keratinocytes. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells. IL-20 is highly associated with potent inflammatory diseases such as psoriasis, contact hypersensitivity, rheumatoid arthritis, and atherosclerosis.