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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • FC experiment of human PBMCs using 98138-1-RR (same clone as 98138-1-PBS)

    FC experiment of human PBMCs using 98138-1-RR (same clone as 98138-1-PBS)

    1x10^6 untreated or PMA, Ionomycin and Brefeldin A treated human PBMCs were intracellularly stained with 0.25 ug Anti-Human IL-4 Rabbit Recombinant Antibody (98138-1-RR, Clone: 240794E11) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (APC-65569, Clone: OKT3). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98138-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98138-1-RR

    Affinity and Kinetic Characterization of 98138-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98138-1-RR against Human IL-4 were performed. The affinity constant is below 1 pM.

Anti-Human IL-4 Rabbit Recombinant Antibody, PBS Only

IL-4 Uni-rAbTM Recombinant Antibody for FC (Intra)
Cat No. 98138-1-PBS

产品说明书

CloneNo. 240794E11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC (Intra)

别名

IL4, interleukin 4, IL 4, BSF-1, B-cell stimulatory factor 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98138-1-PBS targets IL-4 in FC (Intra) applications and shows reactivity with human samples.

经测试应用 FC (Intra) Application Description
经测试反应性 human
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 interleukin 4
别名 IL4, interleukin 4, IL 4, BSF-1, B-cell stimulatory factor 1
计算分子量 153 aa, 17 kDa
GenBank蛋白编号BC070123
基因名称 IL-4
Gene ID (NCBI) 3565
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP05112
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.