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Anti-Human IL-7Ra/CD127 Rabbit Recombinant Antibody, PBS Only

IL-7Ra/CD127 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

240749H2

Cat no : 98074-1-PBS

Print datasheet

Synonyms

CD127, 240749H2, IL 7RA, IL 7R subunit alpha, IL 7R alpha

验证数据展示

  • FC experiment of human PBMCs using 98074-1-RR (same clone as 98074-1-PBS)

    FC experiment of human PBMCs using 98074-1-RR (same clone as 98074-1-PBS)

    1x10^6 human PBMCs were stained with CoraLite® Plus 647 Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (CL647-65569, Clone: OKT3) and 0.25 ug Anti-Human IL-7Ra/CD127 Rabbit Recombinant Antibody (98074-1-RR, Clone:240749H2), or Isotype Control. Cells were not fixed. This data was developed using the same antibody clone with 98074-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98074-1-RR (same clone as 98074-1-PBS)

    FC experiment of human PBMCs using 98074-1-RR (same clone as 98074-1-PBS)

    1x10^6 human PBMCs were stained with 0.25 ug Anti-Human IL-7Ra/CD127 Rabbit Recombinant Antibody (98074-1-RR, Clone:240749H2) (red), or Isotype Control(blue). Cells were not fixed. This data was developed using the same antibody clone with 98074-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98074-1-RR

    Affinity and Kinetic Characterization of 98074-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98074-1-RR against Human IL-7Ra/CD127 were performed. The affinity constant is 4.57 nM.

产品信息

The immunogen of 98074-1-PBS is IL-7Ra/CD127 Fusion Protein expressed in E. coli.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name interleukin 7 receptor
Synonyms CD127, 240749H2, IL 7RA, IL 7R subunit alpha, IL 7R alpha
Calculated Molecular Weight52 kDa
GenBank Accession NumberAAC83204.1
Gene Symbol CD127
Gene ID (NCBI) 3575
ENSEMBL Gene IDENSG00000168685
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP16871-1(I66T, V138I)
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD127, also known as IL-7R subunit alpha (IL-7RA), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells. IL-7R is a heterodimer composed of CD127 and the common-γ chain receptor (CD132). IL-7R plays critical roles in lymphocyte development and homeostasis. CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP).