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IL-2RG Polyclonal antibody

IL-2RG Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 11409-1-AP

Print datasheet

Synonyms

IL2RG, IL-2 receptor subunit gamma, IL 2RG, IL 2R subunit gamma, IL 2 receptor subunit gamma

验证数据展示

  • WB analysis using 11409-1-AP

    WB analysis using 11409-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 11409-1-AP (IL2RG antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inJurkat cells, K-562 cells, Raji cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11409-1-AP targets IL-2RG in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen IL-2RG fusion protein Ag1911 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name interleukin 2 receptor, gamma (severe combined immunodeficiency)
Synonyms IL2RG, IL-2 receptor subunit gamma, IL 2RG, IL 2R subunit gamma, IL 2 receptor subunit gamma
Calculated Molecular Weight 369 aa, 42 kDa
Observed Molecular Weight 64-70 kDa
GenBank Accession NumberBC014972
Gene Symbol IL2RG
Gene ID (NCBI) 3561
RRIDAB_2264645
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP31785
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The interleukin-2 receptor (IL-2R) is a heterotrimeric receptor consisting of three subunits, alpha (IL-2RA), beta (IL-2RB), and gamma (IL-2RG). IL-2RG, also known as CD132, is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in the gene of IL-2RG cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

实验方案

Product Specific Protocols
WB protocol for IL-2RG antibody 11409-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols