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验证数据展示

  • Cytometric bead array standard curve of MP50242-1

    Cytometric bead array standard curve of MP50242-1

    Cytometric bead array standard curve of MP50242-1, IL4R/IL-4RA/CD124 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-2-PBS. Standard:Ag28411. Range: 1.563-100 ng/mL.

  • Cytometric bead array standard curve of MP50242-2

    Cytometric bead array standard curve of MP50242-2

    Cytometric bead array standard curve of MP50242-2, IL4R/IL-4RA/CD124 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-4-PBS. Detection antibody: 67051-3-PBS. Standard:Ag28411. Range: 0.781-100 ng/mL.

  • Cytometric bead array standard curve of MP50242-3

    Cytometric bead array standard curve of MP50242-3

    Cytometric bead array standard curve of MP50242-3, IL4R/IL-4RA/CD124 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-5-PBS. Standard:Ag28411. Range: 0.195-100 ng/mL.

IL-4RA/CD124 Monoclonal antibody, PBS Only (Capture/Detector)

IL-4RA/CD124 Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Cat No. 67051-3-PBS

产品说明书

CloneNo. 3F12E8

宿主/亚型

Mouse / IgM

种属反应性

human

应用

Cytometric bead array, Indirect ELISA

别名

IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67051-3-PBS targets IL-4RA/CD124 as part of a matched antibody pair:

MP50242-1: 67051-3-PBS capture and 67051-2-PBS detection (validated in Cytometric bead array)

MP50242-2: 67051-4-PBS capture and 67051-3-PBS detection (validated in Cytometric bead array)

MP50242-3: 67051-3-PBS capture and 67051-5-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 IL-4RA/CD124 fusion protein Ag28411 种属同源性预测
宿主/亚型 Mouse / IgM
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 4 receptor
别名 IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein
计算分子量 90 kDa
GenBank蛋白编号NM_000418
基因名称 IL-4R
Gene ID (NCBI) 3566
偶联类型 Unconjugated
形式 Liquid
纯化方式Euglobulin precipitation
UNIPROT IDP24394
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.