验证数据展示
经过测试的应用
| Positive WB detected in | mouse lung tissue, mouse heart tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
28422-1-AP targets ILT-3/LILRB4 in WB, IF, ELISA applications and shows reactivity with Human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IF |
| 经测试反应性 | Human, mouse |
| 文献引用反应性 | mouse |
| 免疫原 | ILT-3/LILRB4 fusion protein Ag28928 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| 别名 | CD85K, HM18, ILT 3, ILT3, ILT-3, LILRB4, LILRB5, LIR 5, LIR5 |
| 计算分子量 | 448 aa, 49 kDa |
| 观测分子量 | 49 kDa |
| GenBank蛋白编号 | BC026309 |
| 基因名称 | LILRB4 |
| Gene ID (NCBI) | 11006 |
| RRID | AB_3086050 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q8NHJ6 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
LILRB4 is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades, thus playing an important role in physiological and pathological conditions, including autoimmune diseases, microbial infections, and cancers.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ILT-3/LILRB4 antibody 28422-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |