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验证数据展示

  • WB analysis using 67663-1-Ig (same clone as 67663-1-PBS)

    WB analysis using 67663-1-Ig (same clone as 67663-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67663-1-Ig (IMPDH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 67663-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast hyperplasia using 67663-1-Ig (same clone as 67663-1-PBS)

    IHC staining of human breast hyperplasia using 67663-1-Ig (same clone as 67663-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast hyperplasia tissue slide using 67663-1-Ig (IMPDH2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67663-1-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 67663-1-Ig (same clone as 67663-1-PBS)

    IF Staining of A549 using 67663-1-Ig (same clone as 67663-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed A549 cells using IMPDH2 antibody (67663-1-Ig, Clone: 1B1G8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67663-1-PBS in a different storage buffer formulation.

  • WB analysis of A549 using 67663-1-Ig (same clone as 67663-1-PBS)

    WB analysis of A549 using 67663-1-Ig (same clone as 67663-1-PBS)

    WB result of IMPDH2 antibody (67663-1-Ig; 1:40000; incubated at room temperature for 1.5 hours) with sh-Control and sh-IMPDH2 transfected A549 cells. This data was developed using the same antibody clone with 67663-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

IMPDH2 Monoclonal antibody, PBS Only

IMPDH2 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 67663-1-PBS

产品说明书

CloneNo. 1B1G8

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

IMP dehydrogenase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67663-1-PBS targets IMPDH2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 Human, mouse, rat
免疫原 IMPDH2 fusion protein Ag17170 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 IMP (inosine monophosphate) dehydrogenase 2
别名 IMP dehydrogenase 2, IMPD 2, IMPD2, IMPDH 2, IMPDH II, IMPDH2
计算分子量 514 aa, 56 kDa
观测分子量 56 kDa
GenBank蛋白编号BC012840
基因名称 IMPDH2
Gene ID (NCBI) 3615
RRIDAB_2882860
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP12268
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IMPDH2, also named as IMPD2, belongs to the IMPDH/GMPR family. It is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. IMPDH2 is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. (PMID:21181270)