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IMUP Polyclonal antibody

IMUP Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 25561-1-AP

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Synonyms

C19orf33, H2RSP, HAI 2 related small protein, IMUP, IMUP 1, IMUP 2



经过测试的应用

Positive WB detected inEC109 cells, A549 cells, SGC-7901 cells, HeLa cells, L02 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

25561-1-AP targets IMUP in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen IMUP fusion protein Ag22218 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chromosome 19 open reading frame 33
Synonyms C19orf33, H2RSP, HAI 2 related small protein, IMUP, IMUP 1, IMUP 2
Calculated Molecular Weight 106 aa, 11 kDa
Observed Molecular Weight20 kDa, 22 kDa
GenBank Accession NumberBC060319
Gene Symbol IMUP
Gene ID (NCBI) 64073
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9GZP8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Immortalization up-regulated protein (IMUP), also known as C19orf33 or H2RSP, was first identified in SV40-immortalized fibroblasts and includes two isoforms, IMUP-1 and IMUP-2 (PMID: 14981917; 35142956). It is found primarily in the nucleus (PMID: 11606055). IMUP is reportedly upregulated in many cancer cells and tissues and its overexpression is associated with tumorigenicity and cell-cycle acceleration (PMID: 16962562; 35142956; 22886722). This polyclonal antibody raised against 1-106 aa of human IMUP can recognize both IMUP-1 and IMUP-2. The apparent molecular determined by SDS-PAGE might be due to post-translational modifications or anomalous migration behavior (PMID: 11080599).

实验方案

Product Specific Protocols
WB protocol for IMUP antibody 25561-1-APDownload protocol
Standard Protocols
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