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INSRR Polyclonal antibody

INSRR Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 55112-1-AP

Print datasheet

Synonyms

INSRR, IR related receptor, IRR

验证数据展示

  • WB analysis of mouse kidney using 55112-1-AP

    WB analysis of mouse kidney using 55112-1-AP

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55112-1-AP (INSRR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse kidney tissue, human brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55112-1-AP targets INSRR in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name IR related receptor
Synonyms INSRR, IR related receptor, IRR
Calculated Molecular Weight 144 kDa
Observed Molecular Weight 150-155 kDa
GenBank Accession NumberNM_014215
Gene Symbol INSRR
Gene ID (NCBI) 3645
RRIDAB_10859077
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP14616
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

INSRR, also named as IRR, belongs to the protein kinase superfamily, Tyr protein kinase family and INS receptor subfamily. It probably binds an INS related protein and has a tyrosine-protein kinase activity. It phosphorylates the INS receptor substrates IRS-1 and IRS-2. INSRR is a heterotetrameric transmembrane receptor composed of two alpha and two beta chains linked by disulfide bonds. INSRR shares high homology with the INS (IR) and the IGF-1R, but doesn't bind any of IR and IGF-1R known ligands. The antibody is specific to INSRR.

实验方案

Product Specific Protocols
WB protocol for INSRR antibody 55112-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols