验证数据展示
经过测试的应用
Positive WB detected in | HeLa cells, HuH-7 cells, MCF-7 cells |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:1000-1:5000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
31038-1-AP targets INTS8 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | INTS8 fusion protein Ag34627 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | integrator complex subunit 8 |
Synonyms | C8orf52, FLJ20530, INT8, integrator complex subunit 8, INTS8, Protein kaonashi 1 |
Calculated Molecular Weight | 111 kDa |
Observed Molecular Weight | 111 kDa |
GenBank Accession Number | BC136754 |
Gene Symbol | INTS8 |
Gene ID (NCBI) | 55656 |
RRID | AB_3669824 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q75QN2 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Integrator complex subunit 8 (INTS8) is one of the major components of RNA polymerase II and has been demonstrated to be involved in the cleavage of small nuclear RNAs and transcriptional processes (PMID: 34880328). INTS8 was robustly increased in neurodevelopmental diseases and numerous tumors. High INTS8 expression has a tight correlation with poor prognosis in multi-cancers (PMID: 30881114). Western blot analysis detected INTS8 at an apparent molecular mass of 111 kDa.
实验方案
Product Specific Protocols | |
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WB protocol for INTS8 antibody 31038-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |