验证数据展示
产品信息
11657-1-PBS targets INTS9 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | INTS9 fusion protein Ag2226 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | integrator complex subunit 9 |
别名 | RC 74, INTS 9, Int9, CPSF2L, CPSF2 |
计算分子量 | 658 aa, 74 kDa |
观测分子量 | 74 kDa |
GenBank蛋白编号 | BC025267 |
基因名称 | INTS9 |
Gene ID (NCBI) | 55756 |
RRID | AB_2127514 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q9NV88 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
INTS9, also known as Integrator Complex Subunit 9, is part of the core cleavage module consisting of INTS4/INTS9/INTS11 involved in processing small nuclear RNA (snRNA) molecules. It is a subunit of the Integrator complex, which comprises 15 subunits (including INTS6L), and plays a crucial role in the 3' end processing of snRNAs. By participating in the biogenesis of snRNAs, INTS9 contributes to the proper functioning of the spliceosome, a cellular machinery responsible for the accurate splicing of precursor messenger RNA (pre-mRNA) molecules. This process is essential for generating mature messenger RNA (mRNA), which is subsequently translated into functional proteins.