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Species Reactivity
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Species Reactivity
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验证数据展示

  • IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

    IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 83847-5-RR (IQUB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83847-5-PBS in a different storage buffer formulation.

  • IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

    IHC staining of mouse testis using 83847-5-RR (same clone as 83847-5-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 83847-5-RR (IQUB antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83847-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83847-5-RR

    Affinity and Kinetic Characterization of 83847-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83847-5-RR against Human IQUB were performed. The affinity constant is 0.144 nM.

IQUB Recombinant antibody, PBS Only

IQUB Uni-rAbTM Recombinant Antibody for IHC, ELISA
Cat No. 83847-5-PBS

产品说明书

CloneNo. 240957A11

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA

别名

IQ motif and ubiquitin-like domain-containing protein, 240957A11

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

83847-5-PBS targets IQUB in IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 IQUB fusion protein Ag19507 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 IQ motif and ubiquitin domain containing
别名 IQ motif and ubiquitin-like domain-containing protein, 240957A11
计算分子量 791 aa, 93 kDa
观测分子量 70 kDa
GenBank蛋白编号BC128181
基因名称 IQUB
Gene ID (NCBI) 154865
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ8NA54
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IQUB (IQ motif and ubiquitin domain containing) was discovered in 2002,4 which was located on chromosome 7q31.32 and its encoded protein mainly contained 2 domains, ubiquitin-like domain and IQ domain. IQUB had apparently higher expression in breast cancer than that in normal tissues, suggesting that it may act an important role in the occurrence and development of breast cancer (PMID: 29968965). IQUB is a critical RS1 adaptor in mouse sperm flagella, and is critical for sperm motility and fertilization (PMID: 36417862).