• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84076-3-RR (same clone as 84076-3-PBS)

    WB analysis using 84076-3-RR (same clone as 84076-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84076-3-RR (ISLR2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84076-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84076-3-RR

    Affinity and Kinetic Characterization of 84076-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84076-3-RR against Human ISLR2 were performed. The affinity constant is below 1 pM.

ISLR2 Recombinant antibody, PBS Only

ISLR2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84076-3-PBS

产品说明书

CloneNo. 241227D6

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

LINX, Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein, KIAA1465, Immunoglobulin superfamily containing leucine-rich repeat protein 2, 241227D6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

产品信息

84076-3-PBS targets ISLR2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ISLR2 fusion protein Ag20505 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 immunoglobulin superfamily containing leucine-rich repeat 2
别名 LINX, Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein, KIAA1465, Immunoglobulin superfamily containing leucine-rich repeat protein 2, 241227D6
计算分子量 745 aa, 79 kDa
观测分子量79 kDa, 130 kDa
GenBank蛋白编号BC152429
基因名称 ISLR2
Gene ID (NCBI) 57611
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ6UXK2
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2), also known as LINX. It is expected to be located in cell membrane and the protein is mainly expressed in brain and testis. While the first knockout mouse had impaired development of the internal capsule and no hydrocephalus, a much more recent independent knockout mouse was shown to additionally have severe hydrocephalus. Although the mechanism remains unclear, it may be related to the role of ISLR2 in reorganizing the cytoskeleton of developing neurons (PMID: 30483960). The calculated molecular weight of ISLR2 is 79 kDa, this target has phosphorylation modification and glycosylation modification. And the 130 kDa band is glycosylated (PMID: 29739947).