Insulin(cattle)

Insulin cattle (Insulin from bovine pancreas) 是一种在胰腺 β 细胞中产生的两链多肽激素,在很多哺乳动物细胞培养体系中用作生长因子。

CAS号

11070-73-8

分子式

C254H377N65O75S6

主要靶点

IGF-1R

仅限科研使用

Cat No : CM04710

Print datasheet

Synonyms

Insulin from bovine pancreas|牛胰岛素|胰岛素



产品信息

Insulin cattle (Insulin from bovine pancreas) is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells。It has often been used as growth supplement in culturing cells.

CAS号 11070-73-8
分子式 C254H377N65O75S6
主要靶点 IGF-1R
主要通路 蛋白酪氨酸激酶
分子量 5733.49
纯度 , 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Insulin from bovine pancreas|牛胰岛素|胰岛素

体外活性

Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. And the α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 μg/mL of medium generally.

溶解度

H2O:11 mg/mL (1.92 mM),ultrasonic and adjust pH to 2 with HCl

参考文献

1.Yousefi R, et al. Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreaticinsulin. J Biomol Struct Dyn. 2016;34(2):362-75.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2