Irigenin

Irigenin 可通过特异性和选择性地阻断 Extra Domain A 域的 C-C 环上α9β1和α4β1整合素结合位点,介导其抗转移作用。它是一种先导化合物,通过增强胃癌细胞中促凋亡分子的表达来敏化 TRAIL 诱导的凋亡,具有抗癌作用。

CAS号

548-76-5

分子式

C18H16O8

主要靶点

NF-κB|Integrin

仅限科研使用

Cat No : CM02939

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Synonyms



产品信息

Irigenin has antifungal activity.

CAS号 548-76-5
分子式 C18H16O8
主要靶点 NF-κB|Integrin
主要通路 NF-κB信号通路|细胞骨架
分子量 360.32
纯度 99.71%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

溶解度

DMSO:65 mg/mL(180.4 mM)

参考文献

1.Kwang Seok Ahn, et al. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E2 production in murine macrophage RAW 264.7 cells. 2006, 78(20): 2336-2342.
2.Xu L L, Zhang Y, Chai Y, et al. Differentiation of belamcandae rhizoma and iridis tectori rhizoma by thin-layer chromatography and high-performance liquid chromatography[J]. World Journal of Traditional Chinese Medicine. 2021

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2