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Isoxazole

Isoxazole (1,2-oxazole) 是乙酰胆碱酯酶 (AChE) 的抑制剂。异恶唑的配体结合并抑制 Sxc-反转运蛋白。

CAS号

288-14-2

分子式

C3H3NO

主要靶点

AChR

仅限科研使用

Cat No : CM15015

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Synonyms

1,2-oxazole|异恶唑

验证数据展示

  • CAS No.: 288-14-2

    Isoxazole
    CAS#: 288-14-2

产品信息

Isoxazole is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.

CAS号 288-14-2
分子式 C3H3NO
主要靶点 AChR
主要通路 神经科学
分子量 69.06
纯度 99.50%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 1,2-oxazole|异恶唑

溶解度

DMSO:50 mg/mL (723.98 mM)

参考文献

1.Gutiérrez M,et al.Isoxazoles: synthesis, evaluation and bioinformatic design as acetylcholinesterase inhibitors.The Journal of pharmacy and pharmacology 2013-11-5
2.Matti AA,et al.Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology model.Bioorg Med Chem Lett. 2013 Nov 1;23(21):5931-5. Matti AA1

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2