KCNA6 Polyclonal antibody

KCNA6 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 31900-1-AP

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Synonyms

Protein Phosphatase 1, Regulatory Subunit 96, PPP1R96, Potassium voltage-gated channel subfamily A member 6, Kv1.6, Human Brain Potassium Channel-2



经过测试的应用

Positive WB detected inDaudi cells, Jurkat cells, Raji cells, TT cells, U2OS cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31900-1-AP targets KCNA6 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen KCNA6 fusion protein Ag35654 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name potassium voltage-gated channel, shaker-related subfamily, member 6
Synonyms Protein Phosphatase 1, Regulatory Subunit 96, PPP1R96, Potassium voltage-gated channel subfamily A member 6, Kv1.6, Human Brain Potassium Channel-2
Calculated Molecular Weight59 kDa,529aa
Observed Molecular Weight65 kDa
GenBank Accession NumberNM_002235.3
Gene Symbol KCNA6
Gene ID (NCBI) 3742
RRIDAB_3670137
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
UNIPROT IDP17658
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The Shaker-like Kv1 potassium channel family comprises 8 α subunits (Kv1.1-Kv1.8), which are key regulators of neuronal excitability in mammals (PMID: 7842011; 9581771; 22612818). Potassium voltage-gated channel subfamily A member 6 (KCNA6, also known as HBK2, Kv1.6, and PPP1R96) is a multi-pass membrane protein that is mainly expressed in the central and peripheral nervous system (PMID: 12042352; 8872310). The concentration of the Kv1.6 channel in the cell membrane can modulate the kinetic properties of Kv1.6-induced K+ current (PMID: 14575698).

实验方案

Product Specific Protocols
WB protocol for KCNA6 antibody 31900-1-APDownload protocol
Standard Protocols
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