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KCND3 Recombinant antibody

KCND3 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

240578F12

Cat no : 83640-5-RR

Print datasheet

Synonyms

KV4.3, KSHIVB, KCND3S, KCND3L, 240578F12

验证数据展示

  • WB analysis of rat brain using 83640-5-RR

    WB analysis of rat brain using 83640-5-RR

    rat brain tissue were subjected to SDS PAGE followed by western blot with 83640-5-RR (KCND3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 83640-5-RR

    Affinity and Kinetic Characterization of 83640-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83640-5-RR against Human KCND3 were performed. The affinity constant is 0.712 nM.

经过测试的应用

Positive WB detected inrat brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

83640-5-RR targets KCND3 in WB, ELISA applications and shows reactivity with human, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, rat
Immunogen KCND3 fusion protein Ag22183 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name potassium voltage-gated channel, Shal-related subfamily, member 3
Synonyms KV4.3, KSHIVB, KCND3S, KCND3L, 240578F12
Calculated Molecular Weight 655 aa, 73 kDa
Observed Molecular Weight 73 kDa
GenBank Accession NumberBC113477
Gene Symbol KCND3
Gene ID (NCBI) 3752
RRIDAB_3671251
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9UK17
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KCND3 gene encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 gene defect causes both cardiological and neurological syndromes. Kv4.3 contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

实验方案

Product Specific Protocols
WB protocol for KCND3 antibody 83640-5-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols