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KCND3 Recombinant antibody

KCND3 Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

240578F12

Cat no : 83640-5-RR

Print datasheet

Synonyms

KV4.3, KSHIVB, KCND3S, KCND3L, 240578F12

验证数据展示

  • WB analysis of rat brain using 83640-5-RR

    WB analysis of rat brain using 83640-5-RR

    rat brain tissue were subjected to SDS PAGE followed by western blot with 83640-5-RR (KCND3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 83640-5-RR

    Affinity and Kinetic Characterization of 83640-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83640-5-RR against Human KCND3 were performed. The affinity constant is 0.712 nM.

经过测试的应用

Positive WB detected inrat brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

83640-5-RR targets KCND3 in WB, ELISA applications and shows reactivity with human, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, rat
Immunogen KCND3 fusion protein Ag22183 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name potassium voltage-gated channel, Shal-related subfamily, member 3
Synonyms KV4.3, KSHIVB, KCND3S, KCND3L, 240578F12
Calculated Molecular Weight 655 aa, 73 kDa
Observed Molecular Weight 73 kDa
GenBank Accession NumberBC113477
Gene Symbol KCND3
Gene ID (NCBI) 3752
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9UK17
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KCND3 gene encodes the voltage-gated potassium ion channel subfamily D member 3, a six trans-membrane protein (Kv4.3), involved in the transient outward K+ current. KCND3 gene defect causes both cardiological and neurological syndromes. Kv4.3 contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

实验方案

Product Specific Protocols
WB protocol for KCND3 antibody 83640-5-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols