KCNE4 Polyclonal antibody
KCNE4 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA and More (2)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | L02 cells |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
18289-1-AP targets KCNE4 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | WB, ELISA Application Description |
| Cited Applications | WB, IF, IHC |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | potassium voltage-gated channel, Isk-related family, member 4 |
| Synonyms | KCNE4, MinK related peptide 3, MIRP3 |
| Calculated Molecular Weight | 18 kDa |
| Observed Molecular Weight | 25-30 kDa |
| GenBank Accession Number | NM_080671 |
| Gene Symbol | KCNE4 |
| Gene ID (NCBI) | 23704 |
| RRID | AB_2132300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WWG9 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
KCNE4, also named as MIRP3 and MGC2035, is a membrane protein belongs to a family of single transmembrane domain proteins known to have dramatic effect on the gating of certain potassium channels. KCNE4 is expressed strongly in heart, skeletal muscle and kidney. Electrophysiological studies show that human KCNE4 modulates the activation of the KCNQ1 channel.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for KCNE4 antibody 18289-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Cell Sci The C-terminal domain of Kv1.3 regulates functional interactions with the KCNE4 subunit. | ||
FASEB J The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3. |