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验证数据展示

  • WB analysis using 22158-1-AP

    WB analysis using 22158-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 22158-1-AP (KCNMA1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

KCNMA1 Polyclonal antibody

KCNMA1 Polyclonal Antibody for WB, ELISA
Cat No. 22158-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

别名

KCa1.1, K(VCA)alpha, hSlo, BKTM, BKCA alpha

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inmouse brain membrane protein, rat brain membrane protein

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22158-1-AP targets KCNMA1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 KCNMA1 fusion protein Ag17802 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
别名 KCa1.1, K(VCA)alpha, hSlo, BKTM, BKCA alpha
计算分子量 1236 aa, 138 kDa
观测分子量~130 kDa
GenBank蛋白编号BC137115
基因名称 KCNMA1
Gene ID (NCBI) 3778
RRIDAB_3669389
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ12791
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Calcium-activated potassium channel subunit alpha-1 also known as large conductance calcium-activated potassium channel, subfamily M, alpha member 1 (KCa1.1), or BK channel alpha subunit, is a voltage-gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes. KCNMA1 is widely distributed in human cell membranes, especially in muscle cells and neurons. They regulate the excitability of cells through sensitivity to calcium ions (Ca²⁺) and voltage, thereby affecting key physiological processes such as muscle contraction and nerve signal transduction.

实验方案

Product Specific Protocols
WB protocol for KCNMA1 antibody 22158-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols