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KCNQ3 Polyclonal antibody

KCNQ3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 24580-1-AP

Print datasheet

Synonyms

BFNC2, EBN2, KCNQ3, KQT like 3, KV7.3

验证数据展示

  • WB analysis using 24580-1-AP

    WB analysis using 24580-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 24580-1-AP (KCNQ3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse brain tissue, rat brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24580-1-AP targets KCNQ3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen KCNQ3 fusion protein Ag20147 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name potassium voltage-gated channel, KQT-like subfamily, member 3
Synonyms BFNC2, EBN2, KCNQ3, KQT like 3, KV7.3
Calculated Molecular Weight 872 aa, 97 kDa
Observed Molecular Weight~90 kDa
GenBank Accession NumberBC128576
Gene Symbol KCNQ3
Gene ID (NCBI) 3786
RRIDAB_3085739
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO43525
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KCNQ3, also named as BFNC2, EBN2 and KV7.3, belongs to the potassium channel family and KQT subfamily. KCNQ3 is probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5, KCNQ3 forms a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Defects in KCNQ3 are the cause of benign neonatal epilepsy type 2 (EBN2).

实验方案

Product Specific Protocols
WB protocol for KCNQ3 antibody 24580-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols