验证数据展示
产品信息
85153-3-PBS targets KCNV1 as part of a matched antibody pair:
MP01872-1: 85153-3-PBS capture and 85153-2-PBS detection (validated in Cytometric bead array)
MP01872-2: 85153-3-PBS capture and 85153-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| 经测试应用 | WB, Cytometric bead array, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | KCNV1 fusion protein Ag3376 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | potassium channel, subfamily V, member 1 |
| 别名 | 242865E3, HNKA, KCNB3, KV2.3, KV8.1 |
| 计算分子量 | 500 aa, 56 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC028739 |
| 基因名称 | KCNV1 |
| Gene ID (NCBI) | 27012 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q6PIU1 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Potassium voltage-gated channel subfamily V member 1 (KCNV1, also known as Kv8.1) is a voltage-gated potassium channel that plays a role in the repolarization phase of the action potential (PMID: 39003683). It is involved in regulating neuronal excitability and is essential for maintaining normal electrical signaling in the nervous system (PMID: 38911266). The function of KCNV1 may also include inhibiting specific types of outwardly rectifying potassium channels (PMID: 8670833).