KDM2A Polyclonal antibody

KDM2A Polyclonal Antibody for WB, IP, ELISA
Cat No. 24311-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, ELISA and More (3)

CXXC8, F box protein FBL7, F box protein Lilina, F box/LRR repeat protein 11, FBL11, FBL7, FBXL11, JHDM1A, KDM2A, KIAA1004, LILINA, lysine (K) demethylase 2A, Lysine specific demethylase 2A

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inJurkat cells, NIH/3T3 cells
Positive IP detected inHeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24311-1-AP targets KDM2A in WB, IP, IF, IHC, CoIP, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, ELISA Application Description
文献引用应用WB, IP, IF, IHC, CoIP
经测试反应性 human, mouse
文献引用反应性human
免疫原 KDM2A fusion protein Ag19448 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 lysine (K)-specific demethylase 2A
别名 CXXC8, F box protein FBL7, F box protein Lilina, F box/LRR repeat protein 11, FBL11, FBL7, FBXL11, JHDM1A, KDM2A, KIAA1004, LILINA, lysine (K) demethylase 2A, Lysine specific demethylase 2A
计算分子量 1162 aa, 133 kDa
观测分子量 126 kDa
GenBank蛋白编号BC064360
基因名称 KDM2A
Gene ID (NCBI) 22992
RRIDAB_2879488
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y2K7
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KDM2A(Lysine-specific demethylase 2A) is also named as CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004 and belongs to the JHDM1 histone demethylase family. It is required to maintain the heterochromatic state, and playing a role in epigenetic silencing. KDM2A is one of the four subunits of the E3 ubiquitin protein ligase complex (SCF) with SKP1, CUL1, RBX1, Fbox protein bringing ubiquitin conjugating enzymes to substrates recruited by F-box.

实验方案

Product Specific Protocols
WB protocol for KDM2A antibody 24311-1-APDownload protocol
IP protocol for KDM2A antibody 24311-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IF,CoIP

Cell Oncol (Dordr)

Hepatitis B virus core protein stabilizes RANGAP1 to upregulate KDM2A and facilitate hepatocarcinogenesis

Authors - Hong-Juan You
humanWB

J Cell Mol Med

Circular RNA circFOXO3 regulates KDM2A by targeting miR-214 to promote tumor growth and metastasis in oral squamous cell carcinoma.

Authors - Yilong Ai
humanWB

J Cell Physiol

The Ubiquitin Ligase SCF(FBXW7α) Promotes ATA3 Degradation.

Authors - Nan Song
humanIP, WB

Cell Rep

Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor.

Authors - Mei Yang
humanWB,IHC

Cell Death Dis

CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1

Authors - Wenting Song
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