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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85168-1-RR (same clone as 85168-1-PBS)

    WB analysis using 85168-1-RR (same clone as 85168-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85168-1-RR (KIR2DL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85168-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85168-1-RR

    Affinity and Kinetic Characterization of 85168-1-RR

    Biolayer interferometry (BLl) kinetic assays of 85168-1-RR against Human KIR2DL1 were performed. The affinity constant is 37.9 nM.

KIR2DL1 Recombinant antibody, PBS Only

KIR2DL1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85168-1-PBS

产品说明书

CloneNo. 242070D11

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

242070D11, CD158 antigen-like family member A, CD158a, Killer cell immunoglobulin-like receptor 2DL1, Natural killer-associated transcript 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

85168-1-PBS targets KIR2DL1 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
别名 242070D11, CD158 antigen-like family member A, CD158a, Killer cell immunoglobulin-like receptor 2DL1, Natural killer-associated transcript 1
计算分子量 39 kDa
观测分子量45 kDa
GenBank蛋白编号BC069344
基因名称 KIR2DL1
Gene ID (NCBI) 3802
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP43626
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1, also known as CD158A and NKAT1) is an inhibitory receptor of NK cells, with β-arrestin 2 mediated recruitment of the tyrosine phosphatases SHP-1 and SHP-2 to KIR2DL1 and facilitated downstream inhibitory signaling (PMID: 18604210). The effector function of NK cells expressing KIR2DL1 or KIR2DS1 is highly influenced by genetic variability and is calibrated by co-expression of additional NK receptors and cognate HLA-C2 ligands (PMID: 31024561).